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TOP STORY OF THE MONTH (December, 2014)

Fri December 19, 14

Tue December 16, 14

The effect of wild card designations and rare alleles inforensic DNA database searches - Forensic article feed - RSS
Forensic DNA databases are powerful tools used for the identification of persons of interest in criminal investigations. Typically, they consist of two parts: (1) a database containing DNA profiles of known individuals and (2) a database of DNA profiles associated with crime scenes. The risk of adventitious matches between crime scene profiles and the profiles of innocent people increases as the number of profiles in a database grows and as more data is shared between various forensic DNA databases, e.g.

Quadrupole time-of-flight mass spectrometry for life science research analysis announced by Bruker - Forensic Media News - RSS
Bruker Corporation (NASDAQ: BRKR) announced today, the evolution of their maXis™ line of ultrahigh-resolution quadrupole time-of-flight (UHR-qTOF) mass spectrometers, bringing industry-leading resolution and mass accuracy to the liquid chromatography, time-of-flight MS market space.
Sat December 13, 14

A comparison of four methods for PCR inhibitor removal - Forensic article feed - RSS
Currently, in the field of forensic science, the polymerase chain reaction (PCR) technology is widely used in DNA analysis of forensic cases. However, biological samples collected from crime scenes often contain various PCR inhibitors that can interfere with the PCR amplification, and this makes forensic DNA testing face huge challenges. Therefore, the removal of PCR inhibitors from the extracts prior to the PCR amplification is vital for successful forensic DNA typing. To cope with the PCR inhibitors, a simple approach is to dilute the sample extracts containing PCR inhibitors, which may dilute out the PCR inhibitor in the hope that there is enough remaining DNA in the sample to still develop a full STR profile.
Fri December 12, 14


Thu December 11, 14

Research links increase in sudden cardiovascular death with consumption of cocaine - Forensic Media News - RSS
A joint piece of research conducted by the UPV/EHU, the Basque Institute of Forensic Medicine, and the Biomedical Research Centre Network into Mental Health of the Carlos III Institute of Health links, for the first time, the increase in sudden cardiovascular death with the recent consumption of cocaine. In people in the 19-49 age bracket this risk is quadrupled.

STSI researchers launch study to examine root cause of sudden unexpected death - Forensic Media News - RSS
Researchers at the Scripps Translational Science Institute have launched a clinical trial aimed at cracking one of the toughest mysteries in forensic science -- sudden unexplained death.
Sat December 6, 14

Ancestry informative markers: Inference of ancestry in aged bone samples using an autosomal AIM-Indel multiplex - Forensic article feed - RSS
The ancestry of a forensic evidence contributor, based on ancestry informative marker (AIM) analysis, can provide valuable information [1–7]. Although lineage markers from mitochondrial DNA (mtDNA) and Y chromosome give information on the maternal and paternal ancestries, respectively, they are haploid non-recombinant genetic markers that represent just a very small proportion of the genome. Therefore, the ancestry of admixed or non-admixed individuals is more comprehensively estimated when a selection of recombining autosomal genetic markers is used.
Fri December 5, 14

Inclusion probability with dropout: an operational formula - Forensic article feed - RSS
In forensic genetics, a mixture of two or more contributors to a DNA profile is often interpreted using the inclusion probabilities theory. In this paper, we present a general formula for estimating the probability of inclusion (PI, also known as the RMNE probability) from a subset of visible alleles when dropouts are possible. This one-locus formula can easily be extended to multiple loci using the cumulative probability of inclusion. We show that an exact formulation requires fixing the number of contributors, hence to slightly modify the classic interpretation of the PI.
Last updated : Sun December 21, 14 - 18:34:50




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